The Standard ISO 15189:2022 specifies requirements for quality and competence in medical laboratories. This course gives a structured and comprehensive approach on interpretation of the requirements of ISO 15189:2022 for implementation in a Medical Laboratory. This course includes aspects on planning, managing, conducting and leading the internal audits of in a Medical Laboratory. The revised Standard notably includes perspectives of Risk Management and Point-of-Care Testing (POCT), placing emphasis on effective, timely and efficient Patient Care.